Abstract

MARQUES, Gabriela Franco; BARRETO, Jaison Antônio; SOUSA, Juliana Martins Prazeres  and  BRANDAO, Leticia Stella Gardini. Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy. Hansenol. int. (Online) [online]. 2012, vol.37, n.2, pp. 81-85. ISSN 1982-5161.

The combination of dapsone, rifampicin and clofazimine has proven quite effective in the treatment of multibacillary leprosy, however dapsone is responsible for numerous side effects. We report a case of hepatoxocidade during multidrug therapy, successfully treated with the introduction of alternative treatment with rifampicin, clofazimine and ofloxacin.

Keywords : Leprosy; Leprosy; Multibacillary; Drug Therapy; Combination.