Resumo

BERSUSA, Ana Aparecida Sanches; LOUVISON, Marilia Cristina Prado  e  BONFIM, José Ruben de Alcântara. Treatment of adults with chronic hepatitis C virus genotype 1 with protease inhibitors (boceprevir and telaprevir or). BIS, Bol. Inst. Saúde (Impr.) [online]. 2013, vol.14, n.2, pp. 221-228. ISSN 1518-1812.

It presents systematic reviews and meta-analyzes, and coverage policies on the use of protease inhibitors (boceprevir and telaprevir) to treat adult patients infected with hepatitis C genotype 1, comparing the treatment of peginterferon alfa and ribavirin with peginterferon alfa ribavirin and protease inhibitor. It was shown that the addition of protease inhibitor has significant impact on the sustained virologic outcome.

Palavras-chave : Hepatitis C; Protease Inhibitors; Interferons.